Principal investigator
Shane Browne
Principal Investigator
Angiogenesis · Biomaterials · Gene delivery · Cardiovascular tissue repair
About
Research profile
Shane Browne develops biomaterials and delivery strategies that regulate vascular, immune and stem-cell responses to improve cardiovascular and wound repair.
Expertise
Research interests
Lab members
Shane’s research team
PhD Scholar
Louise Hosty
Louise Hosty is a PhD scholar in TERG developing her research within a collaborative and internationally diverse tissue-engineering community.
Current work
Research projects
Biomaterial scaffolds
Natural-polymer scaffolds engineered to reproduce extracellular-matrix structure, guide cell behaviour and support tissue repair.
7 associated researchers
Explore research areaHydrogels
Injectable, printable and stimuli-responsive hydrogels for controlled delivery, tissue support and next-generation biomedical devices.
6 associated researchers
Explore research areaTargeted therapeutic delivery
Local delivery of drugs, proteins, peptides, bioinorganic ions, nucleic acids and cells from biomaterials and medical devices.
7 associated researchers
Explore research areaGene-activated materials
Non-viral vectors and biomaterial platforms that deliver genes, microRNAs and other nucleic-acid therapeutics at the site of repair.
6 associated researchers
Explore research areaAntimicrobial and immunomodulatory materials
Bioactive materials designed to counter infection, regulate inflammation and create a repair-supportive immune environment.
6 associated researchers
Explore research areaCardiovascular regeneration
Vascular grafts, heart-valve scaffolds, computational models, biosensors and device-based treatments for cardiovascular disease.
5 associated researchers
Explore research areaSkin and wound healing
Hydrogels and multilayered biomaterials that promote angiogenesis, control inflammation and infection, and support chronic-wound repair.
3 associated researchers
Explore research areaAdvanced disease models
Three-dimensional models of cancer, bone infection, osteoporosis, lung disease and other tissue microenvironments for discovery and screening.
7 associated researchers
Explore research areaSelected outputs
Highlighted publications
Laminin 1 enhances the angiogenic and neurogenic potential of collagen-based scaffolds for complex wound healing applications.
Scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation leading to anti-inflammatory, angiogenic and neurogenic responses for wound healing.
Understanding the Impact of Ostomy Dejecta Constituents on Peristomal Skin Health and Models for Its Characterisation
Development of a VEGF-activated scaffold with enhanced angiogenic and neurogenic properties for chronic wound healing applications.
Hyaluronic acid as a versatile building block for the development of biofunctional hydrogels: In vitro models and preclinical innovations.
Extracellular matrix-inspired biomaterials for wound healing.
Industry & translation
Turning research into impact.
TERG works with academic, clinical and industry partners to move biomaterials, devices and regenerative technologies towards patient benefit.
Industry, spin-outs and collaborationContact
Start a conversation.
For research, collaboration and supervision enquiries, email shanebrowne@rcsi.com.
Lab contact details