Principal investigator

Shane Browne

Principal Investigator

Angiogenesis · Biomaterials · Gene delivery · Cardiovascular tissue repair

Email Shane RCSI profile Google Scholar Scopus

About

Research profile

Shane Browne develops biomaterial systems for tissue repair and in-vitro modelling, including cell encapsulation, therapeutic delivery, chronic wounds and other soft-tissue conditions.

Expertise

Research interests

01Angiogenesis

02Biomaterials

03Gene delivery

04Cardiovascular tissue repair

05Drug delivery

06Endothelial-cell biology

07Skin and wound repair

08Stem-cell biology

09Vascular disease

Lab members

Shane’s research team

Browse PI groups

Postdoctoral researchers

Postdoctoral Researcher

Matthew McGrath

Matthew McGrath is a postdoctoral researcher in Shane Browne’s research group at TERG, RCSI.

matthewmcgrath@rcsi.com View profile

Postdoctoral Researcher

Noémie Petit

Noémie Petit is a postdoctoral researcher in Shane Browne’s research group at TERG, RCSI.

noemiepetit@rcsi.ie View profile

PhD researchers

PhD Researcher

Joanne Chang

Joanne Chang is a PhD researcher in Shane Browne’s research group at TERG, RCSI.

yuyinjoannecha23@rcsi.ie View profile

PhD Researcher

Louise Hosty

Louise Hosty is a PhD researcher in Shane Browne’s research group at TERG, RCSI.

louisehosty23@rcsi.com View profile

PhD Researcher

Martina Konecna

Martina Konecna is a PhD researcher in Shane Browne’s research group at TERG, RCSI.

martinakonecna25@rcsi.com View profile

Selected outputs

Highlighted publications

All publications by this PI

2026Biomaterials advancesFeatured

Laminin 1 enhances the angiogenic and neurogenic potential of collagen-based scaffolds for complex wound healing applications.

McGrath M, Palomeque-Chávez JC, O'Connor C, Maughan J, Dervan A, Browne S, O'Brien FJ

Spinal cord, peripheral nerve and neural repair Skin and wound healing Biomaterial scaffolds

DOI Article

2026Bioactive materials

Scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation leading to anti-inflammatory, angiogenic and neurogenic responses for wound healing.

Palomeque Chávez JC, Dobricic M, McGrath M, O'Connor C, McGuire T, Maughan J, Dervan A, Dixon JE, Kearney CJ, Browne S, O'Brien FJ

Gene-activated materials Antimicrobial and immunomodulatory materials Spinal cord, peripheral nerve and neural repair Skin and wound healing Biomaterial scaffolds

DOI Article

2025International Wound Journal

Understanding the Impact of Ostomy Dejecta Constituents on Peristomal Skin Health and Models for Its Characterisation

Mirella A. Ejiugwo, Julie V. Gawenda, Abram D. Janis, Deborah A. McNamara, Sinéad T. O’Donnell and Shane Browne

Skin and wound healing Advanced disease models

DOI

2025Biomaterials science

Development of a VEGF-activated scaffold with enhanced angiogenic and neurogenic properties for chronic wound healing applications.

Palomeque Chávez JC, McGrath M, O'Connor C, Dervan A, Dixon JE, Kearney CJ, Browne S, O'Brien FJ

Spinal cord, peripheral nerve and neural repair Skin and wound healing Biomaterial scaffolds

DOI Article

2025Materials today. Bio

Hyaluronic acid as a versatile building block for the development of biofunctional hydrogels: In vitro models and preclinical innovations.

Petit N, Chang YJ, Lobianco FA, Hodgkinson T, Browne S

Hydrogels Advanced disease models

DOI Article

2024Molecular biology reports

Extracellular matrix-inspired biomaterials for wound healing.

Hosty L, Heatherington T, Quondamatteo F, Browne S

Skin and wound healing Biomaterial scaffolds

DOI Article

Industry & translation

Turning research into impact.

TERG works with academic, clinical and industry partners to move biomaterials, devices and regenerative technologies towards patient benefit.

Industry, spin-outs and collaboration

Contact

Start a conversation.

For research, collaboration and supervision enquiries, email shanebrowne@rcsi.com.

Lab contact details